The Pseudobulbar Affect is characterized by uncontrollable crying or laughing at inappropriate moments. Typically occurring in people with certain neurological conditions or injuries, the brain begins responding to emotions abnormally. Experiencing emotions in an exaggerated manner can lead to inappropriate conduct in social situations, where the condition becomes disruptive to daily livelihood. For example, someone affected may begin crying in response to minor conflicts for several minutes, or experience uncontrollable laughter during mild encounters.

The cover image above, by illustrator Todd Buck, demonstrates the neurological science behind this condition, showcasing the CYP2D6 structures present in areas of the central nervous system. Flying in from the left are Quinidine and Dextromethorphan, which are both used in the drug Nuedextra to target the effect of CYP2D6. Using this visual to further explain the Pseudobulbar Affect helps articulate both the science behind the condition and how treatment works.

For more samples of illustrations designed for pharmaceutical advertising, biotech marketing, medical and consumer publishing, and web-based patient education media, check out Todd Buck’s portfolio.