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So far Core BioVisuals has created 6 blog entries.

What is a Medical Illustrator?

By |June 27th, 2017|Syndicated Content|

What is a Medical Illustrator?
Artistic illustrations are the oldest form of communication. For decades, medical illustrators have created images that have explained anatomy, biology, surgical procedures and sciences that are difficult to conceptualize or physically impossible to see. Medical illustrators can depict cellular processes or internal surgical procedures with dynamic yet comprehensible visuals. As medical practices change and new scientific discoveries are made, medical illustrators adapt to these shifts and provide the necessary visual tools to educate, clarify and solve communication problems in the industry.
The importance of a medical illustrator to have a strong background in artistic, medical and scientific education is crucial to the growing field of medicine and brings enormous value as a professional. The values of a medical illustrator are based on the ability to problem solve, the capability to adapt to challenging situations and the intelligence to innovate explore new ideas to visually communicate.

What is a Medical Illustrator?

Who is a medical illustrator?

A medical illustrator is a highly skilled professional artist with the ability to visually communicate and problem solve. Most medical illustrators have acquired a master’s degree from an accredited graduate program. The experiences gained during the duration of the program contribute to the capacity to find new ways to effectively communicate with a variety of people. Medical illustrators will attend lectures that involve working along side medical students. The course load includes human anatomy, clinical studies and cadaveric dissections that strengthen their knowledge of the human body. Histology and pathology are studied to gain a better understanding of the cellular processes and medical anomalies within the body’s systems.

What is a Medical Illustrator?Problem Solving

With this education and understanding, a medical illustrator possesses the skills to problem solve and communicate at a healthcare professional level. Medical illustrators work with surgeons to illustrate a specific surgical procedure, collaborate with medical legal firms to create illustrations for surgical malpractice trials and they can produce effective visuals for pharmaceutical companies.

Flexibility and Versatility

A medical illustrator’s creative versatility and flexibility help them overcome obstacles. Illustrators can capture a mood, atmosphere or emotion that appeals to a specific audience. This can improve the effectiveness of communications that lack and are limited by text and words. They can illustrate new devices or procedures that are only conceptual and can focus on a certain feature that otherwise would be overlooked. Medical illustrators explore new, innovative ways to create compelling images that fuel a technology driven society. They generate 2D, 3D and interactive visuals that cater to a technology driven society.


As a professional, the value of a medical illustrator is endless. Medical illustrations provide more than a photograph or simple text. As a medical illustrator the abilities to problem solve, be versatile and thrive on new ideas and innovations, makes us indispensable.

Can Gene Editing Techniques Like CRISPR-Cas9 Be Used to Replace Mutated Genes in CF?

By |June 27th, 2017|Syndicated Content|

Can Gene Editing Techniques Like CRISPR-Cas9 Be Used to Replace Mutated Genes in CF?

Changing the Paradigm of CF Healthcare

Can Gene Editing Techniques Like CRISPR-Cas9 Be Used to Replace Mutated Genes in CF?
CRISPR Cas9 Cutting targeted area of DNA
Research in gene editing has begun to demonstrate the possibility of replacing mutated genes through the use of CRISPR-Cas9, which uses a single stranded RNA to guide a nuclease to remove mutated genes in the genome. The CRISPR-Cas9 system holds potential in the development of gene therapies for genetic diseases like cystic fibrosis.
Can Gene Editing Techniques Like CRISPR-Cas9 Be Used to Replace Mutated Genes in CF?
CFTR Gene modifies the channels
preventing choloride passage
Briefly, cystic fibrosis is a genetically inherited disease that results from mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The CFTR gene produces a protein in the cell that functions as a chloride channel in epithelial cells, which line passages in organs throughout the body. Mutations in this gene affect the protein by either reducing the quantity that makes it to the cell membrane, preventing the proper function of the protein on the cell membrane, or both. The resulting dysfunction creates dehydrated mucous in organs, specifically in the lung, which can lead to chronic lung infections, decreased lung function and end stage lung disease.
Therapies to address the underlying cause of CF can be directed to one of three levels in the cell: DNA, RNA, or protein. DNA, which is housed in the nucleus of the cell, contains the necessary instructions to create all the required proteins. The DNA, however, is not free to roam outside of the nucleus and, therefore, the instructions contained in DNA are transcribed or copied into RNA, which travels out of the nucleus where the directions are read to create the necessary protein. Proteins then are the final stage and are pivotal in providing the vital functions for maintaining cell survival.
References Shannon, Stephen. (2015). “Can Gene Editing Techniques Like CRISPR-Cas9 Be Used to Replace Mutated Genes in CF?”. Web. 16 Apr. 2015.

Nanobot Technology | Have We Reached a New Frontier in Dentistry?

By |June 27th, 2017|Syndicated Content|

Nanobot Technology | Have We Reached a New Frontier in Dentistry?

Developments in Technology

Researchers are exploring a long list of ways that nanotechnology could make your visit to the dentist more comfortable, and make the result more effective and attractive.

For example:

  • Delivering therapeutic drugs with nanoparticles or nanorobots that go straight to the source, enabling smaller doses and reducing side effects.
  • Taking high quality images of your mouth with lower levels of radiation.
  • Creating dental implants that mimic the nanoscale features of natural bone and interact better with connecting bone and tissue.
  • Strengthening and whitening teeth by inserting nanomaterials with these properties into the outer layers of enamel.
  • Sending a particular molecule to the site of a dental implant, bone surgery, or tooth decay that tells the cell to initiate repair.
Designing nanorobots to clean teeth and perform other functions, such as sealing exposed channels, called tubules, on teeth that cause hypersensitivity to hot or cold. Other functions might include delivering local anesthesia (no more long needles!) or providing painless, quick orthodontic services.

Dentistry has come a long way from beeswax fillings, with many exciting advances on the horizon. Scientists with backgrounds in nanoscience, chemistry, physics, biology, and medicine are working together, forming companies and research collaborations that aim to turn these possibilities into dentist office realities—realities that will hopefully make your life a little more comfortable, your smile a little brighter, and your teeth healthier and more durable.

Our Reaction

At Core BioVisuals each biomedical illustration serves as a vehicle for knowledge visualization, communicating and transferring a message between the reader and the author. We took on this publication. Advances in technology have increased our ability to manipulate the world around us on an ever-decreasing scale. Nanotechnologies are rapidly emerging within the realm of medicine, and this subfield has been termed nanomedicine. Use of nanoparticle technology has become familiar and increasingly commonplace, especially with pharmaceutical technology. An exciting and promising area of nanotechnological development is the building of nanorobots, which are devices with components manufactured on the nanoscale. With these interesting advances in technology, the interest of the public is always at there. This informational pieces, shows the build/imaginative design of nanobots in the body environment to open up the world of curiosity and excitement about the ongoing projects, as well as inform the general public about the continuous advancements in medicine.
References: Redmond, Kendra. (2016, April). “Nanodentistry: Big Impacts from Small Science”. Anatomical Sciences Education. Web. 06
Sept. 2016.

Botox Injection Simulator | Implementing 3D Simulation Modules in the Education of Dermatology Residents

By |June 27th, 2017|Syndicated Content|

Botox Injection Simulator | Implementing 3D Simulation Modules in the Education of Dermatology Residents


The project will study the effectiveness of integrating 3D simulation modules into resident student practice as an accessory to clinic practice. The use of 3D graphics, videos and interactivity are readily being incorporated into medical education because of the unlimited possibilities for innovations and advances in technology. In many aspects of medical training, 3D simulations lead to improved medical knowledge, increased confidence in procedures, and enhanced performance on retesting the resident/medical student in the field. (Lee 2013)
Botox Injection Simulator | Implementing 3D Simulation Modules in the Education of Dermatology ResidentsRapidly evolving and improving, the purpose of simulators currently bring the sensation of real life clinical scenarios to students without the risk of harming patients. Simulators are not restricted to clinical settings, preferably this projects aims to be used at any time outside of the clinic and class. The use of this project will not replace real clinical practice, but is intended to enhance the student’s ability to realistically and safely practice medicine.

The Process

Botox Injection Simulator | Implementing 3D Simulation Modules in the Education of Dermatology Residents
Cinema 4D Rigged Model
The production process began with heavy research using the materials Dr. Turrentine at Augusta University advised and other helpful resources. The decision was made to use my own facial features for the pilot model. Using 3D scans from the Augusta University Orthodontic Clinic, high resolution images were obtained and imported into Cinema 4D for further modification.Both Cinema 4D and Z Brush were used for the general modeling, rigging, animating and UV mapping of the model.

After multiple revisions, the refined model was imported into Unity. The general interface, consisting of five separate scenes were created in Unity in addition to the interactive assets, buttons and scripts. In order to make the interface seamless, C Sharp and TouchScript scripts were implemented. After completing the interface, the program was then built on both iOS and Windows platforms.
Botox Injection Simulator | Implementing 3D Simulation Modules in the Education of Dermatology ResidentsThe production process overall was quite complex. The intricacies of combining multiple UV maps led to a longer process of refining. There was difficulty in building the scripts, but with the help of the programmer, scripting became easy to learn.

Picture left: The model is seen in Unity platform space. Screen shots are seen from the interactive screen. User is placing injection targets on the patients face.

References Allen, Lauren K., Eagleson, Roy, and de Ribaupierre, Sandrine. (2016, March). “Evaluation of an Online Three-Dimensional Interactive Resource for Undergraduate Neuroanatomy Education”. Anatomical Sciences Education. Web. 17 Sept. 2016. Allergan. (2014). “Virtual Botox: Haptic App Simulates Injecting The Real Thing”. Web. 21 Sept. 2016. Gordon, James A., Pawlowski, John. (2002). “Education On-demand: The Development of a Simulator-based Medical Education Service”. Academic Medicine. Web. 17 Sept. 2016. Graber, Mark A., Wyatt, Christopher, Kasparek, Leah, and Xu, Yinghui. (2005). “Does Simulator Training for Medical Students Change Patient Opinions and Attitudes toward Medical Student Procedures in the Emergency Department?”. Academy of Emergency Medicine. Web. 17 Sept. 2016.Hanke, William C., Moy, Ronald, Roenigk, Randall K., and Roenigk, Jr, Henry H. (2013, October 7). “Current status of surgery in dermatology”. J AM ACAD DERMATOL. Web. 19 Sept. 2016. Lam, Charlene, Crites, Joshua S., Clarke, Jennie T., Miller, Jeffrey J., and Kirby, Joslyn S. (2014). “The use of donated products to train residents to perform injectable cosmetic procedures”. Dermatoethics Consultation. Web. 18 Sept. 2016. Lee, S., Lee, J., Lee, A., Park, N., Lee, S., Song, S., Seo, A., Lee, H., Kim, J.-I., Eoma, K. (2012). “Augmented reality intravenous injection simulator based 3D medical imaging for veterinary medicine”. The Veterinary Journal. Web. 18 Sept. 2016. Okuda, Yashuharu, Bryson, Ethan O., Demaria Jr., Samuel, Jacobson, Lisa, Quinones, Joshua, Shen, Bing, and Levine, Adam I. (2009). “The Utility of Simulation in Medical Education: What Is the Evidence?”. Mount Sinai Journal of Medicine. Web. 21 Sept. 2016. Peterson, Diana, Mlynarczyk, and Gregory S.A. (2016). “Analysis of Traditional Versus Three- Dimensional Augmented Curriculum on Anatomical Learning Outcome Measures”. Anatomical Sciences Education. Web. 21 Sept. 2016. Santan, Sally A., Hemphill, Robin R., Spanier, Cindy M., and Fletcher, Nicholas D. (2005). “‘Sorry, it’s my first time!’ Will patients consent to medical students learning procedures?”. Medical Education. Web. 21 Sept. 2016. Shen, Yunhe, Vasandani, Pankaj, Iyer, Jayesh, Gunasekaran, Arjune, Zhang, Yingchun, Burke, Daniel, Dykstra, Dennis, and Sweet, Robert. (2012). “Virtual Trainer for Intra-Detrusor Injection of Botulinum Toxin to Treat Urinary Incontinence”. Medicine Meets Virtual Reality. Web. 17 Sept. 2016. Surgery Squad (2016). Web. 21 Sept. 2016. Wang, Leo L. (2016, January). “Gunner Goggles: Implementing Augmented Reality into Medical Education”. Studies in Health Technology and Informatics. Web. 17 Sept. 2016.

RBC Functional Deformation | Sickle Cell Disease 3D Interactive Model

By |June 26th, 2017|Syndicated Content|

Today is World Sickle Cell Awareness. Sickle Cell Disease affects millions of people around the world, including both adults and children. It is a potentially fatal disease and, according to the World Health Organization (WHO), is one of the main cause...