The Effects of Inflammatory Mediators in IVD Pain—a Review

The Effects of Inflammatory Mediators in IVD Pain—a Review

A review investigating the role of inflammatory mediators in the degeneration of intervertebral discs (IVD) found that in-vitro disc cells exposed to inflammatory conditions can release cytokines and other neurogenic and angiogenic factors and that these, along with the development of nerve and vessel roots within the fissured annular fibrosis (AF), can contribute to the […]

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