The animation was created for CogRx, a small biotech startup in Pittsburgh. This exciting project brought to life the protein structures CogRx is currently investigating.
From Steffen Visual Effects,
Some proteins that we know interact have yet to be crystallized as bound structures. In order to better understand protein function and the cascade of events that result in cellular process, we work with structural biologists to theorize potential alignments and interactions.
Creating the 3D animation for the beta amyloid beta oligomer required significant research in order to determine viable conformation changes of individual monomers. Referencing Dr. Vijay Pande’s work at Stanford University to simulate AB oligomerization http://www.ncbi.nlm.nih.gov/pubmed/19063575 , our medical animators developed this depiction of an AB oligomer movement.