This brief medical animation by Adriana Lippy describes the pathological process of acute [...]
A research study of GABAergic communication within rodent peripheral sensory ganglia demonstrated that somatosensory pain signals can be transmitted from the peripheral sensory nerves to the central nervous system (CNS). The study further found that necessary proteins required in GABA synthesis were released by sensory neurons and triggered by depolarization. By infusing the sensory ganglia […]
The post Study Indicates Pain Signals Can be Transmitted from the Peripheral Sensory Nerves to the CNS appeared first on Dynamic Disc Designs.
Numerous studies have examined disc volume, height, and fluid flow to more clearly understand the effects and rate of cellular diffusion and nutrient and waste transfer on IVD. However, to date, there have been no significant measurements of the rate at which discs lose fluids during normal activity throughout the day. We know that IVD […]
The post In Vivo MRI Study Examines the Rate of Disc Fluid Loss Over an 8 Hour Day appeared first on Dynamic Disc Designs.
A review 1 of how biochemical and micromechanical events affect the cellular biology and morphology of intravertebral discs (IVD) during physical motion, loading, and compression determined that important interactions between the nucleus pulposus and annular fibrosis altered cells, micromechanical, mechanobiological, and mechanical features. Because previous studies have indicated a strong genetic link in the propensity […]
The post Research into IVD Cell Mechanobiology and the Role of Genetics in IVD Degeneration Necessary appeared first on Dynamic Disc Designs.
Study Finds Prolapse Injury Influenced by Flexion Degree and Level of Hydration, not Rate of Loading
A study 1 of isolated and adapted bovine spinal segments examined the extent to which flexion, hydration, and loading rates were responsible for the breakdown of the nucleus pulpous structure and found that the rate of loading had little effect on disc damage with full annular division. Instead, the degree of flexion and the hydration […]
A 2015 study of 36 chronic pain patients sought to explore the causes of pain-related fear in the hopes of contributing to research that might help practitioners develop avoidance models in the future. The study found that the most common cause of pain-related fear is its inexplicability and unpredictability—because patients could not make any reasonable […]
The post Study Finds Understanding their Pain May Help Lesson Fear in Patients appeared first on Dynamic Disc Designs.
When it comes to pain medication, what you know might hurt you. Research on the nocebo effect 1 suggests that patients who are educated about the potential risks or non-efficacy of the pain drugs they take are at higher risk for developing negative symptoms and less satisfied with the outcome after taking the drug. The […]
The post ‘Nocebo’ Response Should be Considered in Doctor-Patient Communication appeared first on Dynamic Disc Designs.
Here are a series of labeled Professional LxH model pictures to help in the greater understanding of anatomical pain generators (and relievers) when exploring symptoms as they relate to spinal motion. At Dynamic Disc Designs Corp. we believe that careful evaluation of the quality of motion can help in the diagnosis and treatment of back […]