Jackie Heda created this three-part illustration to depict mobilization flare in gout. The artwork features an inflamed joint, an enlarged view showing tophi on, and three stages of typical gout therapy, and the interaction of interleukin-1B & urate crystals with cellular elements that cause inflammation.

Explore Jackie Heda’s body of work through her Medical Illustration Sourcebook portfolio and website: jackieheda.com.